Hi killer_bunny!
You could:
1 - Add shortcuts to your menus with your fav. programs or
2 - Get some tools as bbkeys and bbconf. With them you can config buttons to run applications and easily edit themes or menus entries. For example, with ctrl+alt+section, I open a terminal, with with ctrl+alt+1, open Firebird, with ctrl+alt+2 opens Thunderbird, with ctrl+alt+up/down, volume control up or down. Doing that you won't need use the mouse often, nor running xterm